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High potential & largely derisked investment

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Non-toxic solutions to fight neurodegenerative diseases

SigmaThera is a Biotech company with a unique patented transnosologial approach to fight the major underlying mechanisms of neurodegenerative diseases


INVESTORS INFORMATION ABOUT SIGMATHERA NDD DRUG DEVELOPMENT*: 

1. Urgent need for efficient solutions to fight NDDs

In addition to the devastating part caused by NDDs for patients and their families, the economic disease burden of NDDs is extremely high and there is urgent need to develop solutions to treat & prevent these diseases with efficacy. 
The market is highly demanding and pharmaceutical companies are looking for licensing for innovative and efficient solutions as the number of promising solutions in the pipeline are very poor. 

2. Increasing number of patients world wide. 

Worldwide, NDDs are supposed to double in the next 10-20 years and efficient solutions are even more needed in order to keep our NHS able to avoid dramatic situations in patient care and also state finance. 

3. Our innovative transnosological approach

Our molecule support an innovative approach, as it targets simultaneously major underlying mechanisms of neurodegenerative diseases. SIT161not only targets symptom relief, but has a neuroprotective and disease-modifying action in NDDs that reduces apoptosis but also enhances neurogenesis and synaptogenesis.  

4. High efficacy & Low toxicity: Treatment and prevention market

As our molecule demonstrated both efficacy combined with an exceptional safety profile, we can target the treatment market, but also the prevention market which becomes more and more important. Indeed, all governments and health insurance system are looking for prevention, as this approach is less expensive, and a growing number of biomarkers (genetic and others) for early detection of risk of diseases are validated over the last years and become more and more common. However, prevention and long-term treatments need an exceptional safety profile without any toxicity and SIT161 fits to this necessity.  

5. Low cost for final POC in humans for NDDs and largely derisked situation

As we know exactly the dosage for pre CTA work and also Ph. 1 clinical trial, we can perform those steps in a quick and cost-effective way. Ph. 2 clinical studies for final POC for NDDs in humans can be achieved with an exceptionally low cost and a major valorization of the company. 


*Please note that investments are subject to normal due diligence. 

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